Prospective analysis of perinatal outcome of pregnant women with asymptomatic bacteriuria

Kamlesh Rajeev Chaudhari, Soma Dey, Kushagra Rajeev Chaudhari, Ashwini Satish Sakhalkar


Objective:Isolated case reports describing the utility of Fine Needle Aspiration Cytology (FNAC) in the diagnosis of Lymphocutaneous sporotrichosis are available in the literature. Since Himachal Pradesh in India is a known endemic area for cutaneous sporotrichosis, this study was conducted to assess the utility of FNAC in the detection of fungal spores for the diagnosis of lymphocutaneous sporotrichosis.

Methods: FNAC and biopsy were performed from the nodules and indurated ulcers of fifty clinically diagnosed cases of lymphocutaneous sporotrichosis. Smears were reviewed for cytomorphological findings and were correlated with the histopathological findings. Positive cases were further subjected to culture for confirmation. Results: In our study, the sensitivity and specificity of FNAC in diagnosing lymphocutaneous sporotrichosis were 35% and 100% respectively. The sensitivity and specificity of biopsy in diagnosing lymphocutaneous sporotrichosis were 10% and 100% respectively. All seven cases diagnosed on FNAC were confirmed on fungal culture.

Conclusions: FNAC is an effective, useful and a minimally invasive procedure. FNAC is comparatively better than biopsy in detection of fungal spores in the diagnosis of lymphocutaneous sporotrichosis. With an experienced cytologist, it can be used routinely for the diagnosis for lymphocutaneous sporotrichosis.

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. Zaharopoulos P. Fine-needle aspiration cytologic diagnosis of lymphocutaneous sporotrichosis: A case report. Diagnostic Cytopathology 1999; 20:74-7.

. Farley ML, Fagan MF, Mabry LC, Wallace RJ Jr. Presentation of Sporothrix schenkii in pulmonary cytology specimens. Acta Cytol 1991; 35:389-95.

. Gerhard R, Moscoso PC, Gabbi TVB, Valente NYS. Fine-needle aspiration biopsy of disseminated sporotrichosis: a case report. Diagn Cytopathol 2008; 36:174-7.

. Agarwal A, Hirachand S, Karki S, Upadhyay P. Fine needle asapiration cytology diagnosis of cutaneous sporotrichosis and Review of literature. Sudaneese J Dermatol 2010; 8:1815.

. Fontes PC, Kitakawa D, Carvalho YR, Brando AA, Cabral LA, Almeida JD. Sporotrichosis in an HIV-positive man with oral lesions: a case report. Acta Cytologica 2007; 51:648-50.

. Verma S, Verma GK, Singh G, Kanga A, Shanker V, Singh D, et al. Sporotrichosis in Sub-Himalayan India. PLoS Negl Trop Dis 2012; 6:1673.

. Mahajan VK1, Sharma NL, Sharma RC, Gupta ML, Garg G, Kanga AK. Cutaneous sporotrichosis in Himachal Pradesh, India. Mycoses 2005; 48:25-31.

. Ghosh A, Chakrabarti A, Sharma VK, Singh K, Singh A. Sporotrichosis in Himachal Pradesh (North India). Transactions of the Royal Society of Tropical Medicine and Hygiene 1999; 93: 41-5.

. Segal RJ, Jacobs PH. Sporotrichosis. Int J Dermatol 1979; 18:639.

. Fetter BF, Tindall JP. Cutaneous sporotrichosis: clinical study of nine cases utilizing an improved technique for demonstration of organisms. Arch Pathol 1964; 78:613.

. Marques MEA, Coelho KIR, Sotto MN. Comparison between histochemical and immunohistochemical methods for diagnosis of sporotrichosis. J Clin Pathol 1992; 45:1089



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