Status of Dyslipidemia Management with Statins, in In-patients with known Coronary Artery Disease confirmed by angiographic findings

Vijay T, Baruah DK, Ushakiran P, Sudha J, Sudhakar K, Srinivas A.

Abstract


Aim: To determine the status of dyslipidemia management with statins in In-patients with known Coronary Artery Disease (CAD) confirmed by angiographic findings.

Methods: This study has been conducted in a corporate cardiac centre at Visakhapatnam, Andhra Pradesh. This study is a retrospective analysis of data collected from the electronic medical records in terms of age, sex, CAD status, associated risk factors, statin usage, and lipid parameters.

Results: Among a sample of 92 known CAD in-patients, 81.5% achieved LDL-C goal of <100 mg/dl as recommended by Third Report of the National Cholesterol Education Program (NCEP) Adult Treatment Panel III [ATP III] for CAD and CAD risk equivalents. Success rates among males and females are 79.7% and 85% respectively. 78.2% of 69 patients on Atorvastatin, 85% of 20 patients on Rosuvastatin and 100% of 3 patients on Simvastatin achieved LDL-C goal. If the target LDL-C level is kept at <70 mg/dl as defined as optional goal for very high risk CAD and CAD risk equivalents, the success rate is only 31.5%.

Conclusion: The Success rates for achieving LDL-C goals (<100mg/dl) is satisfactory in this facility. But the major concern in this study is even with desired LDL-C levels 61% of these in-patients suffered with a recurrent CAD leaving an opportunity to reconsider the target LDL-C to still lower levels (<70 mg/dl) which is mentioned just as an optional for very high risk candidates in NCEP ATP-III guidelines. 


Keywords


Coronary artery disease; Dyslipidemia; Statins

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DOI: http://dx.doi.org/10.7439/ijbr.v8i7.4248

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