Factors affecting maternal outcome in antepartum eclampsia in BRD Medical College, Gorakhpur

Vani Aditya, Alka Verma, Ankita Kumari, Reena Srivastav


Background: Eclampsia is still prevalent in India with high maternal mortality.

Aim: To analyse the factors affecting maternal outcome in antepartum eclampsia in BRD Medical College, Gorakhpur.

Method: The present observational prospective study was undertaken in the Department of Obstetrics and Gynecology, BRD Medical College, Gorakhpur from August 2015 to July 2016. Women who presented with antepartum eclampsia were included in the study. Data analysed included various maternal parameters and the outcome of pregnancy.

Results: During the defined period, incidence of antepartum eclampsia was 8.9%. Maternal death occurred in 3.7% of patients. Maternal outcome was significantly affected by numbers of convulsions, convulsion delivery interval, raised systolic and diastolic blood pressures and degree of proteinuria. However, age, parity and religion were not found to have any effect on maternal outcome.

Conclusion: Better antenatal care, early recognition of disease, timely referral, and early initiation of treatment and termination of pregnancy improves outcome of eclampsia patients. Management of eclamptic patient should be performed at tertiary care centres, where ICU facilities, NICU facilities and multidisciplinary units are available.


eclampsia, maternal mortality, incidence, maternal outcome

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. James NM. Hypertension of pregnancy. American College of Obstetrician and Gynaecologist, 2013; Pg 13.

. WHO Reduction of maternal mortality (1999) A joint WHO/ UNEPA/ UNICEF/ World bank statement, Geneva.

. Douglas KA, Redman CWG. Eclampsia in United Kingdom. BJOG 1992; 99:355-6.

. Nobis PN, Hajong A. Eclampsia in India through the Decades. J Obstet Gynecol India 2016; 66; 172-176.

. Singh K, Medhi R, Bhattacharjee AK et al. Book of abstract. 53rd AICOG, Guwahati, 2010; P 17.

. Chandriole N, Singh S, Dhillon B.S. Eclampsia, carehood and management practices at the tertiary hospital in India (ICMR), New Delhi. Book of abstracts AICOG Guwahati; 2010: page 33.

. Pal A, Bhattacharjee R, Bannerjee Ch et al. Maternal mortality over a decade in a referral Medical College Hospital West Bengal. Indian J Perinatal Reprod. Biol 2001; 04: 10-3.

. Swain S, Ohha KN, Prakash A. Maternal and perinatal mortality due to Eclampsia. Indian Pediatr. 1993; 30(6):771- 3.

. Begum MR, Begum A, Quadir E, Akhter S, Shamsuddin L. Eclampsia : Still a problem in Bangladesh. Med Gen Med 2004; 6:52.

. Sunita TH, Desai RM. Eclampsia in a Teaching Hospital 2013. Incidence, clinical profile and response to magnesium sulphate by Zuspans regimen. IOSR-JDMS. 2013; 4(2):1-5.

. Bhalerao A, Kulkarni S, Ghike S, Kawthalkar A, Joshi S, Somalwar S. Eclampsia: Maternal and fetal outcome. J South Asian Feder Obstet Gynae 2013; 5(1): 19- 21.

. Chesley LC. Hypertensive disorders in pregnancy. New York: Appleton. Century Crofts. 1978; 1-628.

. Pannu D, Das B, Hazari P, Shilpa. Maternal and Perinatal Outcome in Eclampsia and factors affecting the outcome: a study in North Indian population. Int J Reprod Contracept Obstet Gynaecol. 2014; 3(2):347- 351.

. Nanda Smiti, Jai Bhagwan Sharma, Nirmal Gulati. Perinatal mortality in Eclampsia. J Obstet Gynaecol Ind 1989; 39: 792-4.

. Menon MKK. The evolution of the treatment of eclampsia. J Obstet Gynaec Brit C Wealth 1961; 68(3):417-26.

. Richard F, Worley. Eclampsia. Progress in Obstetrics and Gynaecology. 3rd edition. John Studd, London: Churchill Livingstone 1984; 183-96.

. Fernando A. Practical guide to high risk pregnancy and delivery. 2nd Edition. USA: Mosby 1998; 183-207.

. Singh S, Behera A. Eclampsia in Eastern India: Incidence, Demographic Profile and response to three Different Anticonvulsant Regimes of Magnesium Sulphate. Internet J Gynecol Obstet. 2010; 15(2): 1-8.

. Ann K. Lal, Weihua Gao, Judith U. Hibbard. Eclampsia. Maternal and Neonatal Outcomes. Pregnancy Hypertension. Int. J Womens Cardiovas Health: 2013; 186-90.

. Zwart J, Richters A, Ory F. Vries J, Bloemenkamp K, Roosemalen J. Eclampsia in Netherlands. Obstet Gynaecol. 2008; 112:820-7.

DOI: https://doi.org/10.7439/ijbr.v8i9.4403


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