Split face comparative study for efficacy of microneedling alone versus microneedling combined with vitamin c in treating facial acne scars

Rajnesh Chakrawarty, Mahendra Kumar Jaiswal


Background: Microneedling a newer treatment modality for facial acne scars induces collagen production through mechanical stimulation of the dermis and leads to the softening of scars, realignment of collagen bundles and stimulation of new collagen. Topical vitamin C have beneficial effect on acne and improves acne scarring when used in conjunction with glycolic acid peels and post-laser resurfacing.

Aims: Split face comparative assessment of the efficacy of microneedling therapy versus microneedling therapy in conjunction with topical vitamin C in facial acne scars.

Materials and Methods: This study was performed on 50 patients having facial acne scars after taking informed written consent. The face was divided into right and left half from midline. On the half of face only microneedling and on other side of face microneedling therapy with topical vitamin C (5% L-ascorbic acid) has been used. A total of three session at 4 weeks interval was done in each patient. Facial scars was assessed clinically to grade the severity of scarring, as per the ECCA grading system.

Results: Gradual improvement in global score & acne scar types after each sitting of Microneedling as well as Microneedling + Topical Vitamin-C observed. Overall mean percentage improvement with Microneedling + Topical Vitamin-C was more than the mean percentage improvement with Microneedling alone.

Conclusion: Microneedling shows significant clinical improvement in the M type scars (rolling), and U type scars (boxcar) and modest improvement in V type scars (ice-pick). Effect of microneedling is enhanced by combining the procedure with application of topical vitamin C.


Microneedling; Microneedling with vitamin c; Post acne scars; Split face study; Dermatology

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DOI: https://doi.org/10.7439/ijbr.v8i11.4445


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