Ulcerprotective activity of ethanolic extract of baccaurea ramiflora and Microcos paniculata on experimental animals

  • Suvendu Saha Department of Pharmacology, Malla Reddy Institute of Pharmaceutical Sciences, Maisammaguda, Dhulapally, Secunderabad, Telangana
  • T. Shivraj Gouda Department of Pharmacology, NET Pharmacy College, Raichur
  • S. Vijaya Srinivas Department of Pharmaceutics, Prasad Institute of Pharmaceutical Sciences, Jangaon, Telangana

Abstract

The current study was planned to evaluate the ulcer protective activity of the leaves of Baccaurea ramiflora and Microcos paniculata. Dried and crushed leaves of Baccaurea ramiflora and Microcos paniculata were defatted with petroleum ether and then extracted with alcohol. The alcoholic extract at the doses of 100 mg/kg, and 200 mg/kg body weight was subjected to evaluation of ulcer protective activities in experimental animal models. The reduction in ulcer index dose dependently in hard liquor induced ulcer and in pylorus ligation induced ulcer, by 100 and 200mg/kg body weight doses respectively by the extracts proving its anti-ulcer activity.

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Published
2017-12-02
Section
Original Research Articles