Antimicrobial resistant gram negative isolates from blood stream infections: A report from BPKIHS

  • Abhilasha Sharma BP Koirala Institute of Health Sciences, Dharan, Nepal
  • Narayan Raj Bhattarai BP Koirala Institute of Health Sciences, Dharan, Nepal
  • Basudha Khanal BP Koirala Institute of Health Sciences
Keywords: Antimicrobial resistance, Blood culture, Gram Negative Bacteria, ESBL

Abstract

Objective: To find out resistance pattern and production of ESBL among gram negative blood culture isolates.

Methods: This study was carried out in Microbiology laboratory, BP Koirala Institute of Health Sciences, Dharan, Nepal from July 2011-June 2012. Altogether 150 gram negative bacteria isolated from cases of blood stream infections were evaluated. Isolation, identification of bacteria, determination of antimicrobial susceptibility pattern and detection of ESBL were done following standard protocol.

Results: Resistance to commonly used antimicrobials were noted in varying frequencies. Most of the isolates were resistant to ampicillin (97%) and sensitive to imipenem (98%). Forty seven percent of isolates were ESBL producers and a substantial number of isolates were resistant to at least 3 routinely used drugs.

Conclusion: The study concluded that high resistance was found among the blood culture isolates and ESBL production was seen in a significant number of isolates.

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Author Biographies

Abhilasha Sharma, BP Koirala Institute of Health Sciences, Dharan, Nepal

Department of Microbioligy

Assistant Professor

Basudha Khanal, BP Koirala Institute of Health Sciences

Professor and HOD

Department of Microbiology

Published
2017-09-30
Section
Original Research Articles