Monoclonal antibodies and its impact on modern health services- A review

  • S. Das Post Graduate Resident, Department of Pharmacology, Govt Medical College Patiala, Punjab
  • V K Sehgal Professor, Department of Pharmacology, Govt Medical College Patiala, Punjab
Keywords: Monoclonal antibodies, Hybridoma technology, Immunoglobulin, Human mAbs, Cell Engineering

Abstract

Recent developments in the ability to manipulate immunoglobulin genes has led to development of monoclonal antibodies directed against therapeutic targets. Nowadays, Monoclonal Antibodies act as useful therapies in case of diseases like Cancer, Autoimmune diseases, Infectious diseases and also in conditions like Transplant rejections. The dream of Monoclonal antibodies has been achieved due to advent of Hybridoma technology in 1975.

Monoclonal antibodies are one of the most upcoming fields in biopharmaceutical sciences. The role they have played has brought a revolution in the sector of health services. Not only as a therapeutic tool, its roleplay has also touched the topics of analysis, purification, enrichment and also in mediation of physiological responses. Today, it is continuing to become a befitting reply to various notorious diseases, for which, health professionals had waited for a long time. The purpose of this manuscript is to bring forward , in brief, the role played by Monoclonal antibodies in health sector, various studies related to this marvellous therpeutic tool and the scope, it carries in the near future, and for many years to come.

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Published
2017-08-30
Section
Review Article